The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public health issue with an increase in mortality and morbidity.Here we report our modelled homo-trimer structure of COVID-19 spike glycoprotein in both closed Bulbs (ligand-free) and open (ligand-bound) conformation, which is involved in host cell adhesion.We also predi
The Jekyll and Hyde of Cellular Senescence in Cancer
Cellular senescence is a state of stable cell cycle arrest that can be triggered in response to various insults and is characterized by distinct morphological hallmarks, gene expression profiles, and the senescence-associated secretory phenotype (SASP).Importantly, cellular senescence is a key component of normal physiology with tumor suppressive f
Inhibitory Performance of Spinach Extract on the Corrosion of Q235 Steel in a Citric Acid System
In order to adapt to the rapid development of green plant extract corrosion inhibitors, spinach extract (SPE) was selected as a corrosion inhibitor shield for Q235 steel in citric acid (CA) environment.SPE was extracted using a simple ethanol reflux method, and its main components, as well as their stability in CA, were confirmed through Fourier tr